How peptide compounds interact with your biology.
A comprehensive reference organized by biological mechanism type — not by compound or category. Understanding mechanisms before compounds gives you the framework to evaluate everything else.
Growth hormone secretagogues stimulate the pituitary gland to produce and release more of your own growth hormone — through two complementary receptor systems. GHRH receptors respond to signals like CJC-1295. Ghrelin receptors respond to secretagogues like Ipamorelin. When both are activated simultaneously, the synergistic growth hormone release exceeds what either achieves alone. The result is elevated IGF-1, enhanced protein synthesis, improved fat metabolism, and accelerated tissue repair — operating entirely within your own endocrine architecture.
Compounds: CJC-1295, Ipamorelin, Sermorelin | Categories: Apex™
Glucagon-like peptides are hormones produced naturally in your gut in response to food. The GLP receptor system regulates insulin secretion in proportion to blood glucose, signals the hypothalamus to reduce appetite, slows gastric emptying to extend satiety, suppresses glucagon to reduce liver glucose output, and enhances fat oxidation as insulin sensitivity improves. The result is a comprehensive recalibration of metabolic signaling — operating through pathways your body already has, restored to a precision that diet and exercise alone often cannot achieve.
Compounds: GLP-1 SM, GLP-2 TRZ, GLP-3 RT | Categories: Equilibra™
Melanocortin receptors — MC1R through MC5R — are distributed throughout the body including the brain, skin, and reproductive tissue. MC1R drives skin pigmentation through melanocyte stimulation. MC3R and MC4R in the hypothalamus govern sexual desire, appetite, and energy balance. MC5R regulates exocrine gland function. PT-141 selectively targets MC3R and MC4R to activate neurological desire pathways. MT-2 activates the full receptor spectrum — producing broader effects including spontaneous arousal, pigmentation, and appetite modulation.
Compounds: PT-141, MT-2 | Categories: Ardore™
The thymus matures T cells — the immune cells that coordinate adaptive immune response — through a complex signaling environment that atrophies with age. Thymic peptides restore this signaling environment, promoting T cell maturation, enhancing natural killer cell activity, modulating inflammatory signaling, supporting dendritic cell function, and improving vaccine response. Thymosin Alpha-1 is the most extensively studied thymic peptide with clinical applications across more than 35 countries.
Compounds: Thymosin Alpha-1, Thymic Bioregulators | Categories: Fortis™, Vitae™
Telomeres — the protective caps at chromosome ends — shorten with each cell division, progressively limiting replicative capacity. Telomerase is the enzyme that maintains and restores telomere length, but its activity naturally declines with age. Epithalon activates telomerase through its interaction with the pineal peptide system, also regulating the epigenome toward more youthful gene expression profiles, providing antioxidant activity, and supporting pineal gland function and the sleep architecture that determines biological aging rate.
Compounds: Epithalon | Categories: Vitae™
Brain Derived Neurotrophic Factor — BDNF — is the primary protein regulating neuroplasticity. It stimulates growth of new neurons, strengthens existing synaptic connections, and supports the structural changes underlying learning and memory. Semax upregulates BDNF significantly — exceeding what exercise alone achieves — while also modulating dopaminergic and serotonergic systems, enhancing cerebral blood flow, reducing neuroinflammation, and improving HPA axis stress response.
Compounds: Semax, Neuropeptides | Categories: Acuity™
GHK-Cu is a naturally occurring human plasma peptide that acts as a broad tissue remodeling signal. It stimulates fibroblast proliferation and collagen synthesis, promotes elastin and glycosaminoglycan production, regulates matrix metalloproteinases to shift the remodeling balance toward net structural gain, provides antioxidant copper complexation, stimulates angiogenesis, modulates anti-inflammatory signaling, and influences the expression of more than 4000 genes relevant to tissue repair. GHK-Cu plasma concentration declines significantly with age — making its restoration directly relevant to skin aging, wound healing, and systemic tissue integrity.
Actin is one of the fundamental proteins involved in cell structure, movement, and regeneration. Thymosin Beta-4 regulates actin polymerization — enabling cells to migrate efficiently to sites of injury or tissue need. This mechanism underlies TB-500's documented effects on tissue repair, wound healing, angiogenesis, and anti-inflammatory activity. The same cellular migration capacity that makes TB-500 effective in acute injury recovery also supports broader immune and regenerative tissue functions.
Compounds: TB-500, Thymosin Beta-4 | Categories: Restore™, Fortis™